Hexacarboxymethyl Dipeptide-12
INCOSPHARM
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0.5% MelaTrepeinTM; 2% 1,2-Hexanediol; 97.5% Water
MELATREPEIN 5000 are produced in melanocytes and transferred to neighboring keratinocytes, where they are naturally degraded by autophagy. However, constant exposure to sunlight or changes in hormonal levels may force cell organelles and enzymes to lose their functions, resulting in slowdown of melanosome degradation. Accumulation of survived melanosomes in keratinocytes result in skin pigmentation. MelaTrepeinTM5000 is a dual targeting solution to prevent or reduce skin pigmentation by activating autophagic process to break down melanosomes already existing in keratinocytes, and by blocking new melanosome uptake into keratinocytes at the same time.
Water, Pentasodium Tetracarboxymethyl Palmitoyl Dipeptide-12, Tripeptide-79, 1,2-Hexanediol
Cabelludin 1200 a proprietary peptides complex, is specifically developed for scalp care. It has a dual-mode of action through which autophagy and β-catenin signaling are activated, and ultimately strengthens barrier functions in scalp skin, relieves local inflammation, and modulates the morphogenesis and regeneration of DP cells. Cabelludin clinically reduces the dandruff symptom and sebum secretion. It also decreases scalp skin redness and TEWL, providing a significant scalp calming effect.
Water, 1,2-Hexanediol, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide-5