Crystalline fructose is a naturally occurring sweetening substance found in fruits, vegetables and honey. It is sweeter than normal sugar, low in glycemic index, slow blood glucose response and slow release of insulin.

Commercially, crystalline fructose is made from corn or sugarcane through enzymatic, purification and crystallization processes. It is widely used as a nutritive sweetener in food and beverage due to its functional properties and health benefits. Depending on the temperature at which the products are being consumed, crystalline fructose is the sweetest naturally occurring sugar of around 1.4 to 1.8 times when compared to sucrose.